Blog de Salud

Nuevos materiales para un envejecimiento activo y saludable

06

Feb 2018

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

Posted by / in Blog Salud, Publicaciones 2017, Publicaciones Destacadas, Publicaciones Nanomedicina, Publicaciones Nanomedicina 2017, Últimas Publicaciones CINN / No comments yet

Humans are increasingly exposed to nanoparticles and, although many of their physiological effects have been described, the molecular mechanisms underlying them are still largely unknown. The present study aimed to determine the possible role of certain epigenetic mechanisms in the cellular response of human lung epithelial cells that are triggered by long-term exposure to titanium dioxide nanoparticles (TiO2NPs) and multi-walled carbon nanotubes (MWCNTs). The results showed that exposure to TiO2NPs had only minor effects on genome-wide DNA methylation. However, we identified 755 CpG sites showing consistent DNA hypomethylation in cells exposed to MWCNTs. These sites were mainly located at low density CpG regions and enhancers, and very frequently on the X chromosome. Our results thus suggest that long-term MWCNT exposure may have important effects on the epigenome.

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15

Jun 2017

La NASA y el Centro de Nanotecnología de El Entrego mandarán ratones al espacio

Posted by / in Blog Salud, Noticias Destacadas, Noticias Nanomedicina / No comments yet

Artículo publicado en el diario La Nueva España el 21 de Mayo de 2017.

El Centro de Investigación en Nanomateriales y Nanotecnología (CINN) estudiará las alteraciones óseas en ratones enviados al espacio. La división de biomedicina del equipamiento de El Entrego, liderada por Mario Fernández Fraga, participa en un proyecto de la NASA orientado a estudiar los efectos de la ingravidez sobre el desarrollo óseo de los astronautas. El trabajo del equipo de Fernández Fraga será clave para determinar si la exposición prolongada a un entorno en el que no existe fuerza gravitatoria –como es el caso de los astronautas que desarrollan su labor en la estación espacial internacional– puede derivar en la aparición de problemas como la artritis o la osteoporosis….

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28

Nov 2016

Japan-Spain Joint Workshop on Nanomedicine Research

Posted by / in Blog Salud, Noticias Destacadas, Noticias Nanocomposites y Nanomateriales Multifuncionales / No comments yet

The CINN has been invited to participate in the Japan-Spain Joint Workshop on Nanomedicine Research that will be held in Madrid on 1st December 2016. This event is being organized by AMED, MINECO, CSIC and ISCIII and will bring together Researchers in scientific fields related with Nanomedicine and policy representatives from Japan and Spain in order to explore possibilities of collaboration.

The CINN will be represented by Prof. Ramón Torrecillas, director of the CINN, who will give an overview of the Nanomedicine Research Lines at the Nanomaterials and Nanotechnology Research Center. This talk will be part of the workshop session on “Nanotechnology applications on regenerative medicine”

 

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