Projects' Portfolio

Current and past research projects

Operational Group: Definition of strategies for the reduction of microbial contamination in meat products

Operational Group: Definition of strategies for the reduction of microbial contamination in meat products

The main objective of this Operational Group is to define possible strategies to modify the materials currently used in the meat industry, giving them bacteriostatic and / or biofilm growth inhibition properties. To this end, potential active antimicrobial materials will be evaluated and their integration in some of the materials usually present in the industry […]

Design and simulation of efficient thermoelectric devices on the nanoscale

Design and simulation of efficient thermoelectric devices on the nanoscale

The DEMETER project aims at designing and modeling new efficient thermoelectric devices at the nanoscale. The project is divided in three parts or work packages. We will study vertical devices in the first part. These comprise van der Waals heterostructures -stacks of two-dimensional (2D) materials stacked together by van der Waals forces-, and hybrid 2D […]

Research group on Nanooncology

Research group on Nanooncology

The project scope includes the manufacture and characterization of oxide nanoparticles, the control of their size, shape, properties of aggregation and functionalization. The project aims to develop and characterize oxide nanoparticles that are able to penetrate tumor tissue effectively and selectively. In addition, it aims to optimize the therapeutic power of the nanoparticles. A strong effort […]

Impact of dietary intervention on tumour immunity-DIgesT

Impact of dietary intervention on tumour immunity-DIgesT

Disease progression can be controlled in cancer patients through the administration of immune checkpoint inhibitors (ICIs). But, ICIs mainly show efficacy in subsets of patients and treatment costs are very high. Here, we use a dietary intervention to counteract cancer-related immune suppression through interfering with metabolic pathways. DIgesT will enable the exciting possibility of integrating cancer therapy with […]

The DNA hydroxymethylomes of colorectal cancer

The DNA hydroxymethylomes of colorectal cancer

Colorectal cancer (CRC) continues to be one of the main health problems world-wide. Its high mortality rates are linked to late diagnosis and, therefore, the development of useful biomarkers to aid in earlier detection is a priority in this disease setting. Epigenetic alterations are key processes both in initiation and progression of this disease. In […]

Crosstalk between DNA methylomes and H4K16 acetylomes in acute myeloid leukemia

Crosstalk between DNA methylomes and H4K16 acetylomes in acute myeloid leukemia

Aberrant DNA methylation is a hallmark of cancer. We previously showed that other epigenetic mark, H4K16ac is also frequently altered in hematopoietic tumors. Our two previous FIS projects allowed the identification of specific enzymes underlying this epigenetic alteration and the mapping of the affected chromatin regions. New preliminary data from our laboratory suggest that the […]

Genome-wide changes of hydroxymethylcytosie during aging in adult stem cells

Genome-wide changes of hydroxymethylcytosie during aging in adult stem cells

To investigate the epigenetic alterations during aging in adult stem cells, we recently finalized a study (Fernandez et al. 2015, Genome Res) in which we used Illumina methylation arrays (Illumina Infinium® Human Methylation 450K BeadChip) to analyze the genome-wide DNA methylation patterns of bone marrow mesenchymal stem cells (MSCs) obtained from individuals of different ages. […]

Research Group of the Principality of Asturias on Nanocomposites and Multifuntional Materials

Research Group of the Principality of Asturias on Nanocomposites and Multifuntional Materials

The project to be developed by the research group aims at the development of monolithic and nanocomposite materials with several critical functionalities using the Spark Plasma Technology (SPS) technology. The research will be focused on: • Materials with optical functionality • Materials with thermal functionality • Materials with mechanical functionality • Implantable ceramic and glass-ceramic […]

Polimeric or inorganic multifunctional nanostructured materials for applications in energy and communication technologies

Polimeric or inorganic multifunctional nanostructured materials for applications in energy and communication technologies

The proposed project aims to develop organic -inorganic nanostructured multifunctional materials for energy storage and communications technology through an easily scalable process. One of the processing routes that will be investigated is a “hierarchical approach” based on the nucleation of nanoparticles onto micrometer sized structures , which act both as a substrate and carrier . […]

Reversal processes of magnetization and propagation of domain walls in nanostructured magnetic systems with magnetic exchange

Reversal processes of magnetization and propagation of domain walls in nanostructured magnetic systems with magnetic exchange

This project has been devoted to the fabrication of nanostructured magnetic systems and to the study of magnetization reversal processes in the presence of lithographically defined antidots in two different kinds of magnetic systems. In the first case, arrays of antidots have been fabricated on ferromagnetic/antiferromagnetic bilayers in order to tune exchange bias effects through […]

Artificially prepared and self- assembled 2D arrays of magnetic nanoelements

Artificially prepared and self- assembled 2D arrays of magnetic nanoelements

In this project, performed in collaboration with University of Porto (Portugal), high- density bidimensional arrays of magnetic nanoelements governed by dipolar interactions have been patterned and studied by Magnetic Force Microscopy (MFM) and magnetooptical kerr effect, as well as by micromagnetic simulations and analytical modeling. The results have revealed the important role of the geometrical […]

Cooperative phenomena in nanostructured hybrid systems

Cooperative phenomena in nanostructured hybrid systems

Consortium: CINN (Coordinator) and Complutense University of Madrid Funding: Spanish Ministry of Science and Innovation (MICINN)                                                         

Hybrid sintering and non-conventional machining of advanced technical ceramics-HYMaCER

Hybrid sintering and non-conventional machining of advanced technical ceramics-HYMaCER

The HYMaCER project, driven by 4 dedicated Hi-Tech SMEs, aims at developing a complete supply chain for large size technical ceramic blanks in order to fulfill their need for economically produced, innovative and difficult to densify technical ceramics, all three parameters which are currently limiting the SMEs’ market expansion. The research will be focused on the fabrication […]

Stand-alone lighting personal system-SPIA

Stand-alone lighting personal system-SPIA

The objective of the SPIA project is to design, develop, test and implement new systems for high visibility aimed to develop a family of stand-alone lighting personal clothing based on smart textiles (photoluminescent and electroluminescent) devices and “energy harvesting” (from piezoelectric or ferromagnetic materials). Consortium: FCC Construcción, Confecciones Novatex, CINN, Fundación ITMA Funding: Spanish Ministry of […]

In vitro and in vivo study of biological interactions at the surface of inorganic materials for dental applications.

In vitro and in vivo study of biological interactions at the surface of inorganic materials for dental applications.

The objective of this project is to develop a new generation of ceramic-ceramic composite materials (Al2O3-ZrO2) and ceramic-metal (biocermet) (zirconia – Nb, Ta , Ti) with hierarchical microstructures (nano -micro- macro) for dental applications by controlling the biological interactions that take place at the surface of such materials. Consortium: CINN (Coordinator), ICMM-CSIC, Universidade de Santiago de […]