Featured Publications

High-impact scientific publications

The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome

Human exposure to nanomaterials and nanoparticles is increasing rapidly, but their effects on human health are still largely unknown. Epigenetic modifications are attracting ever more interest as possible underlying molecular mechanisms of gene–environment interactions, highlighting them as potential molecular targets following exposure to nanomaterials and nanoparticles. Interestingly, recent research has identified changes in DNA methylation, histone post-translational modifications, and noncoding RNAs in mammalian cells exposed to nanomaterials and nanoparticles. However, the challenge for the future will be to determine the molecular pathways driving these epigenetic alterations, the possible functional consequences, and the potential effects on health.

Publication Details

  • Journal:International Journal of Nanomedicine 2016:11 6297–6306
  • Authors: Sierra MI, Valdés A, Fernández AF, Torrecillas R, Fraga MF
  • Article URL

Please select the social network you want to share this page with:

We like you too :)

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec tincidunt dapibus dui, necimas condimentum ante auctor vitae. Praesent id magna eget libero consequat mollis.