The Nanotechnology Unit of the Nanomaterials and Nanotechnology Center was inaugurated on July 2005, and it is located at the Severo Ochoa building of the Scientific - Technical Services in the “Campus del Cristo” of University of Oviedo.

The Nanotechnology Unit offers a wide range of nanofabrication services for nanostructured materials and devices and is focused on two main areas:

• Fabrication of micro-and nanostructures using optical and electron beam lithography techniques

• Characterization of micro-and nanostructures at the nanoscale using scanning microscopy techniques.

Services Offered

Scanning Probe Microscopy

• Scanning Tunneling Microscopy (STM) with pseudo-atomic resolution on metallic surfaces.

• Atomic Force Microscopy (AFM): characterization of the roughness and detection of up to monoatomic steps on metallic or insulating surfaces, observation of biological samples, and characterization of the solid-liquid interface in liquid cell.

• Magnetic Force Microscopy (MFM) for the observation of magnetic domains.

• Lithography by local oxidation on Si substrates.

Nanotec Scanning Probe Microscope

Nanotec Scanning Probe Microscope

Optical Lithography

Definition of circuits and chips in a clean room ambient, with lateral dimensions as small as 1 micron, by ultraviolet radiation of 365 nm and 400 nm.

Quintel EXPO line 4k6 Mask Aligner for Optical Lithography

Quintel EXPO line 4k6 Mask Aligner for Optical Lithography


Electron Beam Lithography

Definition of nanostructures or arrays of nanostructures with lateral sizes as small as 20 nm, on substrates and circuits.

LEO EVO 60 Scanning Electron Microscope with a Raith Elphy Plus electronic lithography system


Reactive Ion Etching and Ion Beam Etching

Reactive Ion Etching (RIE) and Ion Beam Etching (RIBE) to transfer the nanostructures defined by lithography. Plasma energy: 30 - 1000 eV

Kenosistec RIE-RIBE KP 600 PBS system

Edificio Severo Ochoa, Campus de “El Cristo”
C/ Fernando Bonguera s/n, 33006. Oviedo

Head of Laboratory:



The CINN is specialized in the conditioning of raw materials, especially ceramics, to be used in forming and sintering processes. Starting materials can be either micro-sized or nano-sized.

Services Offered

Preparation of Stable Ceramic Slurries

Rheological characterization of the slurries is also performed.

Attrition Milling

The CINN is equiped with several attritors mills for milling ceramic powders. 


CINN's powders processing services include spray drying of ceramic slurries prepared in both aqueous and alcohol media.

Freeze Drying

Avda. de la Vega 4-6

33940. El Entrego

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The CINN is fully equipped to perform dilatometric studies, calcination treatments and both presureless and Spark Plasma Sintering.

Services Offered

Dilatometric Studies

Dilatometric studies allow to determine both dynamic sintering curves and materials' thermal expansion coefficients. The CINN has the equipment necessary to carry out the measures under different conditions:

• Analysis at high temperature (up to 1600ºC) in air

• Analysis at high temperature (up to 1600ºC) under inert atmosphere

• Analysis at high temperature (up to 1600ºC) in vacuum

• Analysis in cryogenic conditions ( down to -150ºC) in He atmosphere

Calcination Processes

Two types of calcination treatments are available:

• Calcination in muffle up to 1200ºC.

• Continuous calcination in a rotary kiln up to 1000°C .


Conventional sintering can be performed in air (temperatures up to 1800 °C) and in a controlled atmosphere (up to 1600 °C).

In adittion the CINN has two Spark Plasma Sintering (SPS) facilities:

• A laboratory equipment for samples with a size up to 80 mm in diameter

• An industrial scale research equipment for the fabrication of blanks up to 400 mm in diameter. Additionally, this equipment allows to carry out sintering in a hybrid Hot-Press / SPS mode.

Poligono de La Florida

33958. Sotrondio

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CINN's facilities include an Instron universal testing machine equipped with a high temperature furnace and also a microhardness tester.

Services Offered

Bending Strength
Compressive Strength
Creep Resistance

Poligono de La Florida

33958. Sotrondio

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Ellipsometry is an optical technique devoted to the analysis of surfaces. It is based on the measurement of the variation of the polarizationstate of light after reflection on a plane surface. The strong advantages of ellipsometry are its non destructive character and easiness of preparation of samples for analysis. 


The system installed at CINN allows performing other additional optical and magneto-optical characterizations such as optical transmittance and Kerr and Farady analysis.

Since 2009, CINN has used ellipsometry and related optical and magneto-optical techniques for the study of a wide variety of materials, both as thin films: metals, semiconductos, dielectrics and bulk materials: dielectrics, metals, composites, ferromagnetics...

Services Offered

Optical characterization by ellipsometry, reflectance, transmittance between 190 and 1.9 microns

The measurement range covers since 190 nm to 2 microns, with a resolution better than 0.5 nm between 190 and 900 nm with the DUV-VIs detector and better than 3 microns between 0.75 and 2 microns with the NIR detector, in both cases with high resolution scanning spectrometers. Alternatively, it is possible to acquire full spectra in much shorter times, around 1 s, between 250 and 990 nm with a CCD detector and a resolution not better than 3 nm and between 0.9 and 1.7 microns with the NIR detector and a resolution not better than 9 nm.

For inhomogeneous samples, for example with a composition gradient, or small size samples, microspots optics are available, which allows analysis of 0.365 x 0.27 mm regions at 75º incidence. Under normal incidence, it is possible to study regions with a spot size below 0.3 mm diameter. Also, samples can be positioned with a precision better than 5 microns.


Magneto-Optical Characterization

It is possible to apply a magnetic field to the samples under study and carry Kerr spectroscopy analysis under 190 nm and 2 microns or Faraday spectroscopy studies in the same spectral range with a precision better than 0.01º.

Dielectric characterization in the frequency range 0.1Hz-8 GHz

Avda. de la Vega 4-6

33940. El Entrego

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The CINN offers tests for biological evaluation of medical devices following methods designed to determine the biological response of mammalian cells in vitro. The biological evaluation of medical devices requires the application of ISO 10993: “Biological evaluation of medical devices”

Services Offered

Citotoxicity Studies

Our laboratory is specialized in test methods to assess the in vitro cytotoxicity of medical devices (ISO 10993-part 5: Test for in vitro cytotoxicity) in the three categories of test: extract, direct contact, indirect contact. The cytotoxicity can be determined by assessments of cell damage by morphological means, measurements of cell damage, measurements of cell growth and measurements of specific aspects of cellular metabolism.

Hemocompatibility Tests

Our lab also offers special test: hemocompatibility test, assessment of apoptosis and activation of immune response.

Hospital Universitario Central de Asturias (HUCA)

Julian Claveria S/N. Edificio Polivalente A

33006. Oviedo

Contact Person: 


The Microbiology Laboratory of the Nanomaterials and Nanotechnology Research Center was set-up in 2010 in response to the need to supplement, from a microbiological point of view, the CINN's on-going research on new inorganic biocidal materials. At present, this Lab also provides testing services to other research centers, companies and institutions.

The Lab staff is specialized in unconventional areas of microbiology such as antimicrobial efficacy studies of surfaces, medical devices, plastics, fibers and fabrics, among others. It also performs analysis of antimicrobial preservatives used in cosmetics, paints and food.

The CINN laboratory is a Biosafety Level 2 (BSL-2) lab full equipped with the instrumental required to carry out a wide variety of standardized antimicrobial tests used in industry (type III biosafety cabinets, incubators, ovens ... ).

Services Offered

Standardized Antimicrobial Tests

• ASTM E2149 Standard Test Method for Determining the Antimicrobial Activity of Antimicrobial Agents Under Dynamic Contact Conditions

• ISO 22196 Measurement of antibacterial activity on plastics and other non-porous surfaces

• ISO 20743 Textiles – Determination of antibacterial activity of antibacterial finished products

• ASTM D2574 Standard Test Method for Resistance of Emulsion Paints in the Container to Attack by Microorganisms

• ISO 20645 Textile fabrics – Determination of antibacterial activity – Agar diffusion plate test


Class II cabinet. Telstar Bio II Advance



Special Tests

Our laboratory also offers antimicrobial efficacy tests adapted to the particular needs of new products in a development stage, especially when standardized tests are inadequate to demonstrate its effectiveness. All tests can be performed against a wide variety of bacteria and fungi, including many clinically relevant microorganisms.

Incubator Mermmet


Avda. de la Vega 4-6

33940. El Entrego

Head of Laboratory: